Zhōu Xǐ 周璽 (d. c. 1510), zì Tiānzhāng 天章, hào Jīngshān 荊山, was a Míng remonstrance official from Lúzhōu Héféi 廬州合肥 (modern Ānhuī). He passed the jìnshì in Hóngzhì bǐngchén 弘治丙辰 (1496) and rose to Lǐkē dū gěishìzhōng 禮科都給事中 (Senior Supervising Secretary of Rites). He was famous for his outspoken impeachments under Hóngzhì and Zhèngdé, including the Fǎwáng zhēnrén 法王真人 (a Tibetan-Buddhist favourite of Wǔzōng), the eunuchs Qí Yuán 齊元 and Miáo Kuí 苗逵, and many senior officials including the Gōngbù shàngshū Cuī Zhìduān 崔志端 and Xióng Chōng 熊翀.

Crossed by Liú Jǐn 劉瑾, Zhōu was beaten to death (tíngzhàng 廷杖, beating on the palace steps) c. 1510 — though one Jiājìng 2 (1523) imperial sacrifice text describes him as having died in retirement. The Sìkù editors note this discrepancy and conjecture it was a contemporary cover-up to disguise the official-execution. After Liú Jǐn’s fall, the Lǐkē Sūn Zhēn 孫楨 memorialized seeking redress; Zhōu was posthumously restored to office and one grandson received the yīn hereditary appointment.

His memorials are preserved in the KR2f0024 Chuíguāng jí 垂光集 in 2 juàn — 13 memorials, of which 7 are from Hóngzhì and 6 from Zhèngdé; the two impeachments of Liú Jǐn are particularly notable. The lower juàn contains posthumous biographical materials, family letters, sacrificial texts, and tomb-inscription. Míng shǐ j. 188 has his biography. CBDB has no confident match for the Héféi Zhōu Xǐ; CBDB id 67576 is a different (Qiānān) Zhōu Xǐ with lifedates 1450–1491.